Nocturnal Hypoglycemia in Type 1 Diabetes: An Assessment of Preventive Bedtime Treatments
نویسندگان
چکیده
منابع مشابه
Hypoglycemia in Type 1 Diabetes
In subjects with type 1 diabetes, autoimmune destruction of pancreatic -cells leads eventually to an absolute requirement for insulin replacement therapy. Insulin delivered exogenously is not subject to normal physiological feedback regulation, so it may induce hypoglycemia even in the presence of an intact counterregulatory response. The average individual with type 1 diabetes experiences abou...
متن کاملFrequency of Diabetic Ketoacidosis and Severe Hypoglycemia in Children with Type 1 Diabetes
Background and Objective: Diabetic ketoacidosis and severe hypoglycemia are common and recurrent acute complications of type 1 diabetes and are associated with high mortality and morbidity. The aim of this study was to determine the frequency of diabetic ketoacidosis and hypoglycemia in children with type 1 diabetes. Methods: In this retrospective cross-sectional study, 480 patients with type 1...
متن کاملType 1 Diabetes and Hypoglycemia
Type 1 Diabetes and the -Cell Matthias von Herrath (La Jolla, CA) received the American Diabetes Association (ADA) 2008 Outstanding Scientific Achievement Award for his research on approaches to -cell–specific immune interventions for type 1 diabetes. He began with a discussion of the evidence of a role of viral infections in the development of type 1 diabetes. In experimental models, viral inf...
متن کاملA Randomized Trial of a Home System to Reduce Nocturnal Hypoglycemia in Type 1 Diabetes
OBJECTIVE Overnight hypoglycemia occurs frequently in individuals with type 1 diabetes and can result in loss of consciousness, seizure, or even death. We conducted an in-home randomized trial to determine whether nocturnal hypoglycemia could be safely reduced by temporarily suspending pump insulin delivery when hypoglycemia was predicted by an algorithm based on continuous glucose monitoring (...
متن کاملTerbutaline and the Prevention of Nocturnal Hypoglycemia in Type 1 Diabetes
OBJECTIVE Bedtime administration of 5.0 mg of the beta(2)-adrenergic agonist terbutaline prevents nocturnal hypoglycemia but causes morning hyperglycemia in type 1 diabetes. We tested the hypothesis that 2.5 mg terbutaline prevents nocturnal hypoglycemia without causing morning hyperglycemia. RESEARCH DESIGN AND METHODS This was a randomized double-blind crossover pilot study (placebo, 2.5 mg...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2006
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2005-2798